Faktör VIII

Faktör VIII (FVIII), anti-hemofilik Faktör (AHF) olarak da bilinen önemli bir kan pıhtılaşma faktörüdür. İnsanlarda, Faktör VIII F8 geni ile birlikte kodlanır.[1][2] Faktör VIII geni X kromozomu üzerinde yer almaktadır.

Ayrıca bakınız

Kaynakça
  1. Toole JJ, Knopf JL, Wozney JM, Sultzman LA, Buecker JL, Pittman DD, Kaufman RJ, Brown E, Shoemaker C, Orr EC (1984). "Molecular cloning of a cDNA encoding human antihaemophilic factor". Nature. 312 (5992). s. 342–7. doi:10.1038/312342a0. PMID 6438528.
  2. Truett MA, Blacher R, Burke RL, Caput D, Chu C, Dina D, Hartog K, Kuo CH, Masiarz FR, Merryweather JP (Ekim 1985). "Characterization of the polypeptide composition of human factor VIII:C and the nucleotide sequence and expression of the human kidney cDNA". DNA. 4 (5). ss. 333-49. doi:10.1089/dna.1985.4.333. PMID 3935400.

Ayrıca bakınız
  • Gitschier J (1991). "The molecular basis of hemophilia A". Ann. N. Y. Acad. Sci. 614 (1 Process in Va). ss. 89-96. doi:10.1111/j.1749-6632.1991.tb43694.x. PMID 1902642.
  • White GC, Shoemaker CB (1989). "Factor VIII gene and hemophilia A". Blood. 73 (1). ss. 1-12. PMID 2491949.
  • Antonarakis SE, Kazazian HH, Tuddenham EG (1995). "Molecular etiology of factor VIII deficiency in hemophilia A". Hum. Mutat. 5 (1). ss. 1-22. doi:10.1002/humu.1380050102. PMID 7728145.
  • Lenting PJ, van Mourik JA, Mertens K (1999). "The life cycle of coagulation factor VIII in view of its structure and function". Blood. 92 (11). ss. 3983-96. PMID 9834200.
  • Saenko EL, Ananyeva N, Kouiavskaia D; ve diğerleri. (2003). "Molecular defects in coagulation Factor VIII and their impact on Factor VIII function". Vox Sang. 83 (2). ss. 89-96. doi:10.1046/j.1423-0410.2002.00183.x. PMID 12201837.
  • Lollar P (2003). "Molecular characterization of the immune response to factor VIII". Vox Sang. 83. Cilt Suppl 1. ss. 403-8. PMID 12617176.
  • Fay PJ (2004). "Activation of factor VIII and mechanisms of cofactor action". Blood Rev. 18 (1). ss. 1-15. doi:10.1016/S0268-960X(03)00025-0. PMID 14684146.
  • Lavigne-Lissalde G, Schved JF, Granier C, Villard S (2005). "Anti-factor VIII antibodies: a 2005 update". Thromb. Haemost. 94 (4). ss. 760-9. doi:10.1160/TH05-02-0118. PMID 16270627.
  • Fang H, Wang L, Wang H (2007). "The protein structure and effect of factor VIII". Thromb. Res. 119 (1). ss. 1-13. doi:10.1016/j.thromres.2005.12.015. PMID 16487577.

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