NOX3
Fonksiyon
NOX3 gibi NADPH oksidazlar, birçok hücre tipinde bulunurlar ve plazma membranı ile ilişkili enzimlerdir. Elektron bağışlayıcısı olarak NADPH kullanarak, oksijenin 1 elektron indirgemesiyle süperoksit üretimini katalize ederler. [OMIM tarafından sağlanır] [2]
Kaynakça
- "Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5". Gene. 269 (1–2): 131-40. Mayıs 2001. doi:10.1016/S0378-1119(01)00449-8. PMID 11376945.
- "Entrez Gene: NOX3 NADPH oxidase 3". 2 Kasım 2008 tarihinde kaynağından arşivlendi.
Konuyla ilgili yayınlar
- Lachgar A, Sojic N, Arbault S, Bruce D, Sarasin A, Amatore C, Bizzini B, Zagury D, Vuillaume M (1999). "Amplification of the inflammatory cellular redox state by human immunodeficiency virus type 1-immunosuppressive tat and gp160 proteins". J. Virol. 73 (2): 1447-52. doi:10.1128/JVI.73.2.1447-1452.1999. PMC 103969 $2. PMID 9882350.
- Kikuchi H, Hikage M, Miyashita H, Fukumoto M (2000). "NADPH oxidase subunit, gp91(phox) homologue, preferentially expressed in human colon epithelial cells". Gene. 254 (1–2): 237-43. doi:10.1016/S0378-1119(00)00258-4. PMID 10974555.
- Cheng G, Ritsick D, Lambeth JD (2004). "Nox3 regulation by NOXO1, p47phox, and p67phox". J. Biol. Chem. 279 (33): 34250-5. doi:10.1074/jbc.M400660200. PMID 15181005. Geçersiz
|doi-access=free(yardım) - Jana A, Pahan K (2004). "Human immunodeficiency virus type 1 gp120 induces apoptosis in human primary neurons through redox-regulated activation of neutral sphingomyelinase". J. Neurosci. 24 (43): 9531-40. doi:10.1523/JNEUROSCI.3085-04.2004. PMC 1955476 $2. PMID 15509740.
- Ueno N, Takeya R, Miyano K, Kikuchi H, Sumimoto H (2005). "The NADPH oxidase Nox3 constitutively produces superoxide in a p22phox-dependent manner: its regulation by oxidase organizers and activators". J. Biol. Chem. 280 (24): 23328-39. doi:10.1074/jbc.M414548200. PMID 15824103. Geçersiz
|doi-access=free(yardım) - Ueyama T, Geiszt M, Leto TL (2006). "Involvement of Rac1 in activation of multicomponent Nox1- and Nox3-based NADPH oxidases" (PDF). Mol. Cell. Biol. 26 (6): 2160-74. doi:10.1128/MCB.26.6.2160-2174.2006. PMC 1430270 $2. PMID 16507994. 9 Ekim 2020 tarihinde kaynağından (PDF) arşivlendi. Erişim tarihi: 6 Ekim 2020.
- Carnesecchi S, Carpentier JL, Foti M, Szanto I (2006). "Insulin-induced vascular endothelial growth factor expression is mediated by the NADPH oxidase NOX3". Exp. Cell Res. 312 (17): 3413-24. doi:10.1016/j.yexcr.2006.07.003. PMID 16949073.
- Nakano Y, Banfi B, Jesaitis AJ, Dinauer MC, Allen LA, Nauseef WM (2007). "Critical roles for p22phox in the structural maturation and subcellular targeting of Nox3". Biochem. J. 403 (1): 97-108. doi:10.1042/BJ20060819. PMC 1828898 $2. PMID 17140397.
- Chen G, Adeyemo AA, Zhou J, Chen Y, Doumatey A, Lashley K, Huang H, Amoah A, Agyenim-Boateng K, Eghan BA, Okafor G, Acheampong J, Oli J, Fasanmade O, Johnson T, Rotimi C (2007). "A genome-wide search for linkage to renal function phenotypes in West Africans with type 2 diabetes". Am. J. Kidney Dis. 49 (3): 394-400. doi:10.1053/j.ajkd.2006.12.011. PMID 17336700.
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